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Both illicit fentanyl and carfentanil are extremely risky opioids that will bring about a quick overdose and death when abused, but carfentanil is a lot more potent than fentanyl. Many doses of the anti-overdose drug naloxone (Narcan) will not be effective to reverse an overdose. Keep on studyingRe: Really Freaked Out!! Fentanyl OD or W/D, Not sure